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Adeno-associated virus vectors transduce primary cells much less efficiently than immortalized cells.

Immortalized cell lines have been used to study infection and replication of adeno-associated virus (AAV) in culture, but primary cells presumably provide a better model for AAV behavior in animals. Here, we have evaluated the ability of AAV vectors to transduce primary and immortalized strains of h...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphov: Halbert, C L, Alexander, I E, Wolgamot, G M, Miller, A D
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1995
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188736/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7853479/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.3.1473-1479.1995
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