Simian immunodeficiency virus SIVmac chimeric virus whose env gene was derived from SIV-encephalitic brain is macrophage-tropic but not neurovirulent.

We inoculated four rhesus macaques with molecularly cloned simian immunodeficiency virus SIVmac239/17E env, a chimeric virus whose env gene was derived from the brain of an SIV-encephalitic macaque. Blood and lymphoid tissues had high frequencies of infected cells. The virus was neuroinvasive, but p...

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Pubblicato in:	J Virol
Autori principali:	Joag, S V, Stephens, E B, Galbreath, D, Zhu, G W, Li, Z, Foresman, L, Zhao, L J, Pinson, D M, Narayan, O
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.1367-1369.1995
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