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The N terminal region of human tau is present in Alzheimer's disease protein A68 and is incorporated into paired helical filaments.

Antibody (Ab) E-1 was raised to the amino terminus (19 to 33 amino acid residues) of human tau. It recognized Alzheimer's disease proteins A68 (MW 60, 64, 68 kd), labeled paired helical filaments, and had no reactivity with tau from rat, mouse, and bovine brains. The results indicate that the N...

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Main Authors: Crowe, A., Ksiezak-Reding, H., Liu, W. K., Dickson, D. W., Yen, S. H.
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886469/
https://ncbi.nlm.nih.gov/pubmed/1721492
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