Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses.

Sequence evolution of the hypervariable region 1 (HVR1) in the N terminus of E2/NS1 of hepatitis C virus (HCV) was studied retrospectively in six chimpanzees inoculated with the same genotype 1b strain, containing a unique predominant HVR1 sequence. Immediately after inoculation, all animals contain...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	van Doorn, L J, Capriles, I, Maertens, G, DeLeys, R, Murray, K, Kos, T, Schellekens, H, Quint, W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188641/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.773-778.1995
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