Genetic drift in hypervariable region 1 of the viral genome in persistent hepatitis C virus infection.

The hypervariable region 1 (HVR1) of the putative second envelope glycoprotein (gp70) of hepatitis C virus (HCV) contains a sequence-specific immunological B-cell epitope that induces the production of antibodies restricted to the specific viral isolate, and anti-HVR1 antibodies are involved in the...

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Autori principali: Kato, N, Ootsuyama, Y, Sekiya, H, Ohkoshi, S, Nakazawa, T, Hijikata, M, Shimotohno, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC236417/
https://ncbi.nlm.nih.gov/pubmed/7518526
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