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Overexpressing Centriole-Replication Proteins In Vivo Induces Centriole Overduplication and De Novo Formation

BACKGROUND: Centrosomes have important roles in many aspects of cell organization, and aberrations in their number and function are associated with various diseases, including cancer. Centrosomes consist of a pair of centrioles surrounded by a pericentriolar matrix (PCM), and their replication is ti...

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Bibliografiske detaljer
Main Authors: Peel, Nina, Stevens, Naomi R., Basto, Renata, Raff, Jordan W.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885955/
https://ncbi.nlm.nih.gov/pubmed/17475495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.04.036
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