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Overexpressing Centriole-Replication Proteins In Vivo Induces Centriole Overduplication and De Novo Formation
BACKGROUND: Centrosomes have important roles in many aspects of cell organization, and aberrations in their number and function are associated with various diseases, including cancer. Centrosomes consist of a pair of centrioles surrounded by a pericentriolar matrix (PCM), and their replication is ti...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885955/ https://ncbi.nlm.nih.gov/pubmed/17475495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.04.036 |
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