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Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes

BACKGROUND: The human genome contains a large number of gene clusters with multiple-variable-first exons, including the drug-metabolizing UDP glucuronosyltransferase (UGT1) and I-branching β-1,6-N-acetylglucosaminyltransferase (GCNT2, also known as IGNT) clusters, organized in a tandem array, simila...

詳細記述

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書誌詳細
主要な著者: Li, Can, Wu, Qiang
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885805/
https://ncbi.nlm.nih.gov/pubmed/17475008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-69
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