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A tractable method for simultaneous modifications to the head and tail of bacteriophage lambda and its application to enhancing phage-mediated gene delivery

There is considerable interest in the use of bacteriophage vectors for mammalian cell gene transfer applications, due to their stability, excellent safety profile and inexpensive mass production. However, to date, phage vectors have been plagued by mediocre performance as gene transfer agents. This...

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Detalhes bibliográficos
Main Authors: Zanghi, Christine N., Sapinoro, Ramil, Bradel-Tretheway, Birgit, Dewhurst, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885665/
https://ncbi.nlm.nih.gov/pubmed/17392341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm146
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