Topoisomerase II, scaffold component, promotes chromatin compaction in vitro in a linker-histone H1-dependent manner

TopoisomeraseII (Topo II) is a major component of chromosomal scaffolds and essential for mitotic chromosome condensation, but the mechanism of this action remains unknown. Here, we used an in vitro chromatin reconstitution system in combination with atomic force and fluorescence microscopic analyse...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hizume, Kohji, Araki, Sumiko, Yoshikawa, Kenichi, Takeyasu, Kunio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2007
Gaiak:
Structural Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885653/
https://ncbi.nlm.nih.gov/pubmed/17430970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm116
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