Topoisomerase II, scaffold component, promotes chromatin compaction in vitro in a linker-histone H1-dependent manner

TopoisomeraseII (Topo II) is a major component of chromosomal scaffolds and essential for mitotic chromosome condensation, but the mechanism of this action remains unknown. Here, we used an in vitro chromatin reconstitution system in combination with atomic force and fluorescence microscopic analyse...

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Bibliografske podrobnosti
Main Authors: Hizume, Kohji, Araki, Sumiko, Yoshikawa, Kenichi, Takeyasu, Kunio
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2007
Teme:
Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885653/
https://ncbi.nlm.nih.gov/pubmed/17430970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm116
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