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Topoisomerase II, scaffold component, promotes chromatin compaction in vitro in a linker-histone H1-dependent manner
TopoisomeraseII (Topo II) is a major component of chromosomal scaffolds and essential for mitotic chromosome condensation, but the mechanism of this action remains unknown. Here, we used an in vitro chromatin reconstitution system in combination with atomic force and fluorescence microscopic analyse...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885653/ https://ncbi.nlm.nih.gov/pubmed/17430970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm116 |
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