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DNA sequencing by MALDI-TOF MS using alkali cleavage of RNA/DNA chimeras
Approaches developed for sequencing DNA with detection by mass spectrometry use strategies that deviate from the Sanger-type methods. Procedures demonstrated so far used the sequence specificity of RNA endonucleases, as unfortunately equivalent enzymes for DNA do not exist and therefore require tran...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885642/ https://ncbi.nlm.nih.gov/pubmed/17426131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm056 |
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