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High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase
Telomerase is a cellular reverse transcriptase, which utilizes an integral RNA template to extend single-stranded telomeric DNA. We used site-specific photocrosslinking to map interactions between DNA primers and the catalytic protein subunit (tTERT) of Tetrahymena thermophila telomerase in function...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885581/ https://ncbi.nlm.nih.gov/pubmed/17494734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703157104 |
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