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Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins

Sec1/Munc18 proteins (SM proteins) bind to soluble NSF attachment protein receptors (SNAREs) and play an essential role in membrane fusion. Divergent modes of regulation have been proposed for different SM proteins indicating that they can either promote or inhibit SNARE assembly. This is in part be...

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Hlavní autoři: Hu, Shu-Hong, Latham, Catherine F., Gee, Christine L., James, David E., Martin, Jennifer L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885578/
https://ncbi.nlm.nih.gov/pubmed/17517664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701124104
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