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Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide

When nerve cells communicate, vesicles from one neuron fuse with the presynaptic membrane releasing chemicals that signal to the next. Similarly, when insulin binds its receptor on adipocytes or muscle, glucose transporter-4 vesicles fuse with the cell membrane, allowing glucose to be imported. Thes...

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Autori principali: Christie, Michelle P., Whitten, Andrew E., King, Gordon J., Hu, Shu-Hong, Jarrott, Russell J., Chen, Kai-En, Duff, Anthony P., Callow, Philip, Collins, Brett M., James, David E., Martin, Jennifer L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382502/
https://ncbi.nlm.nih.gov/pubmed/22670057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116975109
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