Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure

We explored the physiologic role of endothelial cell apoptosis during development by generating mouse embryos lacking the inhibitor of apoptosis protein (IAP) survivin in endothelium. This was accomplished by intercrossing survivin(lox/lox) mice with mice expressing cre recombinase under the control...

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Main Authors: Zwerts, Femke, Lupu, Florea, De Vriese, Astrid, Pollefeyt, Saskia, Moons, Lieve, Altura, Rachel A., Jiang, Yuying, Maxwell, Patrick H., Hill, Peter, Oh, Hideyasu, Rieker, Claus, Collen, Désiré, Conway, Simon J., Conway, Edward M.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2007
主題:
Hemostasis, Thrombosis, and Vascular Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885533/
https://ncbi.nlm.nih.gov/pubmed/17299096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-028068
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