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B-cell development fails in the absence of the Pbx1 proto-oncogene

Pbx1, a homeodomain transcription factor that was originally identified as the product of a proto-oncogene in acute pre-B–cell leukemia, is a global regulator of embryonic development. However, embryonic lethality in its absence has prevented an assessment of its role in B-cell development. Here, us...

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מידע ביבליוגרפי
Main Authors: Sanyal, Mrinmoy, Tung, James W., Karsunky, Holger, Zeng, Hong, Selleri, Licia, Weissman, Irving L., Herzenberg, Leonore A., Cleary, Michael L.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885499/
https://ncbi.nlm.nih.gov/pubmed/17244677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-054213
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