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Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity
Apoptosis in dendritic cells (DCs) can potentially regulate DC homeostasis and immune responses. We have previously observed that inhibition of the Fas signaling pathway in DCs results in spontaneous T-cell activation and the development of systemic autoimmunity in transgenic mice. However, the role...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885484/ https://ncbi.nlm.nih.gov/pubmed/17227827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-056424 |
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