Adaptation to persistent growth in the H9 cell line renders a primary isolate of human immunodeficiency virus type 1 sensitive to neutralization by vaccine sera.

Seven diverse primary isolates of human immunodeficiency virus type 1 (HIV-1) were examined and found to be refractory to neutralization by antisera to recombinant gp120 (rgp120) protein from HIV-1 MN. This stands in marked contrast to the sensitivity exhibited by certain laboratory-adapted viruses....

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Publié dans:	J Virol
Auteurs principaux:	Wrin, T, Loh, T P, Vennari, J C, Schuitemaker, H, Nunberg, J H
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188546/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7983734/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.1.39-48.1995
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