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Association of Structural Changes in the V2 and V3 Loops of the gp120 Envelope Glycoprotein with Acquisition of Neutralization Resistance in a Simian-Human Immunodeficiency Virus Passaged In Vivo

The in vivo passage of a neutralization-sensitive, laboratory-adapted simian-human immunodeficiency virus (SHIV-HXBc2) generated a pathogenic, neutralization-resistant virus, SHIV-HXBc2P 3.2. SHIV-HXBc2P 3.2 differs from SHIV-HXBc2 only in 13 amino acid residues of the viral envelope glycoproteins....

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Bibliografske podrobnosti
Main Authors: Ye, Yongjun, Si, Zhi Hai, Moore, John P., Sodroski, Joseph
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC112479/
https://ncbi.nlm.nih.gov/pubmed/11090196
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