Association of Structural Changes in the V2 and V3 Loops of the gp120 Envelope Glycoprotein with Acquisition of Neutralization Resistance in a Simian-Human Immunodeficiency Virus Passaged In Vivo

The in vivo passage of a neutralization-sensitive, laboratory-adapted simian-human immunodeficiency virus (SHIV-HXBc2) generated a pathogenic, neutralization-resistant virus, SHIV-HXBc2P 3.2. SHIV-HXBc2P 3.2 differs from SHIV-HXBc2 only in 13 amino acid residues of the viral envelope glycoproteins....

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ye, Yongjun, Si, Zhi Hai, Moore, John P., Sodroski, Joseph
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11090196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.24.11955-11962.2000
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