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Structural Basis for the Aldolase and Epimerase Activities of Staphylococcus aureus Dihydroneopterin Aldolase

Dihydroneopterin aldolase (DHNA) catalyzes the conversion of 7,8-dihydroneopterin (DHNP) to 6-hydroxymethyl-7,8-dihydropterin (HP) and also the epimerization of DHNP to 7,8-dihydromonopterin (DHMP). Although crystal structures of the enzyme from several microorganisms have been reported, no structur...

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Detalhes bibliográficos
Main Authors: Blaszczyk, Jaroslaw, Li, Yue, Gan, Jianhua, Yan, Honggao, Ji, Xinhua
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885205/
https://ncbi.nlm.nih.gov/pubmed/17331536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.02.009
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