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Manganese Superoxide Dismutase Protects against 6-Hydroxydopamine Injury in Mouse Brains
Dopaminergic neurons of the substantia nigra are susceptible to toxin-based insults. Intrastriatal injection of 6-hydroxydopamine results in selective toxicity to these neurons. A mechanistic role for reactive oxygen species is supported by observations that antioxidants confer protection from 6-hyd...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885201/ https://ncbi.nlm.nih.gov/pubmed/15755737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M413224200 |
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