Torsemide renal clearance and genetic variation in luminal and basolateral organic anion transporters

AIMS: To investigate the association between torsemide renal clearance and genetic variation in the basolaterally expressed renal organic anion transporters OAT1 and OAT3 and in the luminally situated OAT4. METHODS: We analysed 22 polymorphisms in the OAT coding genes SLC22A6, SLC22A8 and SLC22A11 a...

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Detalhes bibliográficos
Main Authors: Vormfelde, Stefan V, Schirmer, Markus, Hagos, Yohannes, Toliat, Mohammad R, Engelhardt, Sabine, Meineke, Ingolf, Burckhardt, Gerhard, Nürnberg, Peter, Brockmöller, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Pharmacogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885129/
https://ncbi.nlm.nih.gov/pubmed/16934049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02655.x
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