Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism

AIMS: To characterize the demographic and pharmacogenetic factors that influence interpatient variability in the plasma concentrations of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz. METHODS: Data from all samples analyzed for efavirenz in our TDM service in 2002 and 2003 were r...

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Detalhes bibliográficos
Main Authors: Burger, David, van der Heiden, Ilse, la Porte, Charles, van der Ende, Marchina, Groeneveld, Paul, Richter, Clemens, Koopmans, Peter, Kroon, Frank, Sprenger, Herman, Lindemans, Jan, Schenk, Paul, van Schaik, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885008/
https://ncbi.nlm.nih.gov/pubmed/16433869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02536.x
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