Pharmacokinetic–pharmacodynamic modelling of QT interval prolongation following citalopram overdoses

AIMS: To develop a pharmacokinetic–pharmacodynamic model describing the time-course of QT interval prolongation after citalopram overdose and to evaluate the effect of charcoal on the relative risk of developing abnormal QT and heart-rate combinations. METHODS: Plasma concentrations and electrocardi...

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Bibliografiske detaljer
Main Authors: Friberg, Lena E, Isbister, Geoffrey K, Duffull, Stephen B
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2006
Fag:
Pharmacokinetics & Pharmacodynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884996/
https://ncbi.nlm.nih.gov/pubmed/16433872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02546.x
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