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Quantification of infant exposure to celecoxib through breast milk

AIMS: To determine the milk-to-plasma (M/P) concentration ratio of celecoxib, and estimate likely infant exposure. METHODS: Blood and milk were sampled for 48 h after oral administration of celecoxib 200 mg to six lactating volunteers. The M/P ratio was derived from the area under the concentration–...

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Bibliografski detalji
Glavni autori: Gardiner, Sharon J, Doogue, Matthew P, Zhang, Mei, Begg, Evan J
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884977/
https://ncbi.nlm.nih.gov/pubmed/16390357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02520.x
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