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Quantification of infant exposure to celecoxib through breast milk
AIMS: To determine the milk-to-plasma (M/P) concentration ratio of celecoxib, and estimate likely infant exposure. METHODS: Blood and milk were sampled for 48 h after oral administration of celecoxib 200 mg to six lactating volunteers. The M/P ratio was derived from the area under the concentration–...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884977/ https://ncbi.nlm.nih.gov/pubmed/16390357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02520.x |
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