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Dexamethasone as a probe for vinorelbine clearance

AIM: To assess the value of using dexamethasone as an in vivo probe for predicting vinorelbine clearance (CL). METHODS: A population approach (implemented with NONMEM) was used to analyse blood vinorelbine pharmacokinetic data from 20 patients who received a 20-min intravenous infusion of vinorelbin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Puisset, Florent, Dalenc, Florence, Chatelut, Etienne, Cresteil, Thierry, Lochon, Isabelle, Tisnes, Pierre, Roché, Henri
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884916/
https://ncbi.nlm.nih.gov/pubmed/15963093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02384.x
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