A predictive model for exemestane pharmacokinetics/pharmacodynamics incorporating the effect of food and formulation

AIMS: Exemestane (Aromasin®) is an irreversible aromatase inactivator used for the treatment of postmenopausal women with advanced breast cancer. The objective of this study was to evaluate the effect of formulation comparing a sugar-coated tablet (SCT) with a suspension and food on the pharmacokine...

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Detalhes bibliográficos
Main Authors: Valle, Marta, Di Salle, Enrico, Jannuzzo, Maria Gabriella, Poggesi, Italo, Rocchetti, Maurizio, Spinelli, Riccardo, Verotta, Davide
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Pharmacokinetics/Pharmacodynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884784/
https://ncbi.nlm.nih.gov/pubmed/15752382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02335.x
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