Cytotoxicity of acridine compounds for Leishmania promastigotes in vitro.

The effect of mammalian and bacterial topoisomerase II inhibitors on Leishmania promastigotes was studied in vitro. Parasites were incubated with drugs, and cytotoxicity was assessed on the basis of the loss of flagellar motility and cell lysis after 48 h. 9-Aminoacridines, which are structurally re...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Werbovetz, K A, Lehnert, E K, Macdonald, T L, Pearson, R D
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1318684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.495
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