Cytotoxicity of acridine compounds for Leishmania promastigotes in vitro.
The effect of mammalian and bacterial topoisomerase II inhibitors on Leishmania promastigotes was studied in vitro. Parasites were incubated with drugs, and cytotoxicity was assessed on the basis of the loss of flagellar motility and cell lysis after 48 h. 9-Aminoacridines, which are structurally re...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1992
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1318684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.495 |
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