Effect of efavirenz treatment on the pharmacokinetics of nelfinavir boosted by ritonavir in healthy volunteers

AIMS: A once-daily (q.d.) nucleoside-sparing regimen can prevent mitochondrial toxicity, overcome viral resistance and improve compliance. In the present study the effect of efavirenz on the pharmacokinetics and tolerability of once-daily nelfinavir/ritonavir was evaluated in healthy subjects. METHO...

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Autors principals: la Porte, C J L, de Graaff-Teulen, M J A, Colbers, E P H, Voncken, D S, Ibanez, S Marco, Koopmans, P P, Hekster, Y A, Burger, D M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2004
Matèries:
Drug Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884651/
https://ncbi.nlm.nih.gov/pubmed/15563361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02214.x
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