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The effects of renal impairment on the pharmacokinetics and safety of fosfluconazole and fluconazole following a single intravenous bolus injection of fosfluconazole

AIMS: Fosfluconazole is a phosphate prodrug of fluconazole (FLCZ). This study was conducted to investigate the effect of renal impairment on the pharmacokinetics of fosfluconazole and FLCZ, and to assess the safety and toleration of fosfluconazole following a single intravenous bolus injection of fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sobue, Satoshi, Tan, Keith, Layton, Gary, Leclerc, Violette, Weil, Angelika
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884522/
https://ncbi.nlm.nih.gov/pubmed/15151523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02073.x
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