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Study of the parameters of binding of R 61837 to human rhinovirus 9 and immunobiochemical evidence of capsid-stabilizing activity of the compound.

The binding of the antiviral compound R 61837 to human rhinovirus 9 (HRV 9) was studied quantitatively and compared with binding of R 61837 to HRV 9H, a semiresistant variant. For both strains, radiolabelled R 61387 bound to native particles only. The Kd values obtained by Scatchard analysis of satu...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Moeremans, M, De Raeymaeker, M, Daneels, G, De Brabander, M, Aerts, F, Janssen, C, Andries, K
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1318682/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.2.417
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