Effects of a nonpeptide motilin receptor antagonist on proximal gastric motor function

AIM: To assess the effects of the motilin receptor antagonist RWJ-68023 on basal and motilin-stimulated proximal gastric volume. METHODS: Eighteen healthy male volunteers received RWJ-68023 in two different doses or placebo for 135 min. After 45 min, subjects received a motilin infusion for 90 min....

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Detalhes bibliográficos
Main Authors: Kamerling, Ingrid M C, van Haarst, Aernout D, Burggraaf, Jacobus, Schoemaker, Rik C, de Kam, Marieke L, Heinzerling, Hartmut, Cohen, Adam F, Masclee, Ad A M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Pharmacodynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884467/
https://ncbi.nlm.nih.gov/pubmed/15025736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.02034.x
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