Population pharmacokinetics of weekly docetaxel in patients with advanced cancer

AIMS: Previous pharmacokinetic studies of the 3-weekly regimen (100 mg m(−2) every 3 weeks) of docetaxel have shown that docetaxel clearance is affected by liver function, body surface area, age, serum α(1)-acid glycoprotein and cytochrome P450 3A4 (CYP3A4) activity. However, the pharmacokinetics of...

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Bibliografiska uppgifter
Huvudupphovsmän: Slaviero, Kellie A, Clarke, Stephen J, McLachlan, Andrew J, Blair, Elaine Y L, Rivory, Laurent P
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2004
Ämnen:
Pharmacokinetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884416/
https://ncbi.nlm.nih.gov/pubmed/14678339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01956.x
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