Pharmacodynamic characterization of the interaction between the glycoprotein IIb/IIIa inhibitor YM337 and unfractionated heparin and aspirin in humans

AIMS: To investigate the pharmacodynamic interaction of unfractionated heparin (UFH) and acetylic salicylic acid (ASA) on YM337, a monoclonal humanized antibody of the platelet GPIIb/IIIa receptor. METHODS: In a randomized, placebo-controlled study three treatment groups each with six healthy volunt...

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Detalhes bibliográficos
Main Authors: Graff, Jochen, Klinkhardt, Ute, Westrup, Dagmar, Kirchmaier, Carl M, Breddin, Hans Klaus, Harder, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Pharmacodynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884347/
https://ncbi.nlm.nih.gov/pubmed/12919181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2003.01873.x
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