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No clinically significant pharmacokinetic interactions between voriconazole and indinavir in healthy volunteers

AIMS: Voriconazole is a new triazole antifungal agent, and is metabolized by the cytochrome P450 isoenzymes CYP2C9, CYP2C19 and to a lesser extent by CYP3A4. Protease inhibitors, such as indinavir, are also metabolized by cytochrome P450 (mainly CYP3A4). As these drugs are likely to be coadministere...

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Bibliografiska uppgifter
Huvudupphovsmän: Purkins, Lynn, Wood, Nolan, Kleinermans, Diane, Love, Edward R
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884318/
https://ncbi.nlm.nih.gov/pubmed/14616416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.02001.x
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