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The effect of ethinyloestradiol and levonorgestrel on the CYP2C19-mediated metabolism of omeprazole in healthy female subjects

AIMS: To study the effect of an oral contraceptive (OC) formulation containing ethinyloestradiol and levonorgestrel (LNG) (combination OC) or LNG alone on the CYP2C19-mediated hydroxylation of omeprazole in healthy females. METHODS: This was an open crossover study with three phases. In phase one, 1...

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Main Authors: Palovaara, Sanna, Tybring, Gunnel, Laine, Kari
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884281/
https://ncbi.nlm.nih.gov/pubmed/12895199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01868.x
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