Polymorphic hydroxylation of perhexiline in vitro

AIMS: The aims of this study were to examine the in vitro enzyme kinetics and CYP isoform selectivity of perhexiline monohydroxylation using human liver microsomes. METHODS: Conversion of rac-perhexiline to monohydroxyperhexiline by human liver microsomes was assessed using a high-performance liquid...

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Detalhes bibliográficos
Main Authors: Sørensen, L B, Sørensen, R N, Miners, J O, Somogyi, A A, Grgurinovich, N, Birkett, D J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Short Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884253/
https://ncbi.nlm.nih.gov/pubmed/12814462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01805.x
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