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Polymorphic hydroxylation of perhexiline maleate in man.

Long term perhexiline maleate therapy causes peripheral neuropathy and hepatic damage in certain subjects. An association between these adverse reactions and a genetically determined relative inability to hydroxylate debrisoquine has been described. This association could indicate either that the ef...

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Detalhes bibliográficos
Main Authors: Cooper, R G, Evans, D A, Whibley, E J
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1049202/
https://ncbi.nlm.nih.gov/pubmed/6694182
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