Phenotyping CYP3A using midazolam in cancer and noncancer Asian patients

AIMS: To investigate CYP3A activity in cancer and noncancer Asian patients using midazolam and to reveal possible alternative traits for phenotyping CYP3A. METHODS: Intravenous midazolam 2.5 mg or 2.5–8 mg was administered to 27 cancer and 24 noncancer patients, respectively. Plasma was sampled at 0...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, How Sung, Goh, Boon Cher, Fan, Lu, Khoo, Yok Moi, Wang, Lingzhi, Lim, Robert, Ong, Ai Bee, Chua, Charlotte
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2003
Konular:
Drug Disposition
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884211/
https://ncbi.nlm.nih.gov/pubmed/12630977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01767.x
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