Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity

The aromatase-knockout (ArKO) mouse provides a useful model to examine the role that estrogens play in development and homeostasis in mammals. Lacking a functional Cyp19 gene, which encodes aromatase, the ArKO mouse cannot synthesize endogenous estrogens. We examined the adipose depots of male and f...

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Autors principals: Jones, Margaret E. E., Thorburn, Anne W., Britt, Kara L., Hewitt, Kylie N., Wreford, Nigel G., Proietto, Joseph, Oz, Orhan K., Leury, Brian J., Robertson, Kirsten M., Yao, Shenggen, Simpson, Evan R.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18833/
https://ncbi.nlm.nih.gov/pubmed/11070087
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