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Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity

The aromatase-knockout (ArKO) mouse provides a useful model to examine the role that estrogens play in development and homeostasis in mammals. Lacking a functional Cyp19 gene, which encodes aromatase, the ArKO mouse cannot synthesize endogenous estrogens. We examined the adipose depots of male and f...

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Main Authors: Jones, Margaret E. E., Thorburn, Anne W., Britt, Kara L., Hewitt, Kylie N., Wreford, Nigel G., Proietto, Joseph, Oz, Orhan K., Leury, Brian J., Robertson, Kirsten M., Yao, Shenggen, Simpson, Evan R.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC18833/
https://ncbi.nlm.nih.gov/pubmed/11070087
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