Beryllium presentation to CD4(+) T cells underlies disease-susceptibility HLA-DP alleles in chronic beryllium disease

Chronic beryllium disease results from beryllium exposure in the workplace and is characterized by CD4(+) T cell-mediated inflammation in the lung. Susceptibility to this disease is associated with particular HLA-DP alleles. We isolated beryllium-specific T cell lines from the lungs of affected pati...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Fontenot, Andrew P., Torres, Michaelann, Marshall, William H., Newman, Lee S., Kotzin, Brian L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050177/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220430797
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