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Beryllium presentation to CD4(+) T cells underlies disease-susceptibility HLA-DP alleles in chronic beryllium disease

Chronic beryllium disease results from beryllium exposure in the workplace and is characterized by CD4(+) T cell-mediated inflammation in the lung. Susceptibility to this disease is associated with particular HLA-DP alleles. We isolated beryllium-specific T cell lines from the lungs of affected pati...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Fontenot, Andrew P., Torres, Michaelann, Marshall, William H., Newman, Lee S., Kotzin, Brian L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18830/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050177/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220430797
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