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Zidovudine–didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells

Drug combinations that include nucleoside reverse transcriptase inhibitors (NRTIs) are remarkably effective in preventing maternal-viral transmission of HIV during pregnancy. However, there may be potential long-term risks for children exposed in utero. Examination of the genotoxic and mutagenic eff...

Täydet tiedot

Tallennettuna:
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Meng, Quanxin, Walker, Dale M., Olivero, Ofelia A., Shi, Xiaochu, Antiochos, Brendan B., Poirier, Miriam C., Walker, Vernon E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2000
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18821/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058153/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220203197
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