Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro.

The L enantiomer of 2',3'-dideoxycytidine (DDC) was recently shown to inhibit selectively human immunodeficiency virus type 1 (HIV-1) in vitro. In the current study, the potent anti-HIV activity of L-DDC was confirmed and extended to several HIV-1 and HIV-2 strains in various cell culture systems, i...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Gosselin, G, Schinazi, R F, Sommadossi, J P, Mathé, C, Bergogne, M C, Aubertin, A M, Kirn, A, Imbach, J L
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8092827/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.6.1292
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