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Rifampin for therapy of experimental pneumococcal meningitis in rabbits.

Rifampin at a maximally effective dose was less active than ceftriaxone (both drugs at 10 mg/kg of body weight.h) in a rabbit model of pneumococcal meningitis (delta log10 CFU/ml.h, -0.40 +/- 0.13 versus -0.77 +/- 0.18; P < 0.01). The bactericidal activity of rifampin decreased at concentrations in...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Nau, R, Kaye, K, Sachdeva, M, Sande, E R, Täuber, M G
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188176/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8067762/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.5.1186
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